This book consists of 33 chapters in eight independent parts covering various details of drug discovery and development through regulatory. The purpose of this guidance is to provide information to. Anticancer drug discovery from serendipity to rational design. Authoritative and uptodate, anticancer drug development guide. Teicher is the author of anticancer drug development guide 5. The book covers many aspects of modern personalized. Teicher, 9781461581543, available at book depository with free delivery worldwide. Principles of anticancer drug development cancer drug discovery and development 2011th edition by elizabeth garrettmayer editor, manuel hidalgo editor, s. Books in pharmacology of anticancer drugs frontiers.
Understanding the reasons and suggesting potential solutions requires a careful analysis of the grand challenges of anticancer drug development. Preclinical screening, clinical trials, and approval cancer drug discovery and development currently unavailable. Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Medicinal chemistry of anticancer drugs, second edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Principles of cancer treatment and anticancer drug development. This book explains the mechanisms of anticancer drug resistance and strategies to overcome it. S9 nonclinical evaluation for anticancer pharmaceuticals fda.
Principles of anticancer drug development cancer drug discovery and development 2011th edition by elizabeth garrettmayer editor, manuel hidalgo editor. The book is to give a view of selected aspects of cancer like its spread in nature, novel anticancer drugs based on chinese herbs or birch bark, novel promising targets of. S9 nonclinical evaluation for anticancer pharmaceuticals march 2010. Authoritative and uptodate, handbook of anticancer pharmacokinetics and pharmacodynamics, 2nd edition provides in one comprehensive and highly practical volume a detailed stepbystep guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to nda submission. Principles of anticancer drug development cancer drug discovery. Medicinal chemistry of anticancer drugs sciencedirect. Relevance of tumor models for anticancer drug development. Principles of anticancer drug development manuel hidalgo. Drawing on the fields of authors draw on the fields of medicinal chemistry, pharmacology, biochemistry, cell biology, molecular biology, and clinical medicine, this timely book is extensively referenced and provides a historical background for the development of each class of drugs.
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